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The first pill version of the blockbuster GLP-1 weight loss drugs has been launched in the US by Novo Nordisk at a lower cost than jab varieties, accelerating a price war in the sector

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Considering that PPG neurons are projecting neurons that have axons containing GLP1 vesicles in many distinct regions of the brain (Figure 1), it seems likely that GLP1 release and action within the brain is locally restricted and regulated like that of other neurotransmitters and modulators

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