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The reason for this precaution is a) the lack of data on KD use in MCAD-deficient patients, and b) the fact that these patients respond well to glucose-based metabolism
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32 The primary outcome for the trial was the first occurrence of a major adverse cardiovascular event (death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke)

Most side effects are temporary, lasting 1 to 3 weeks at each new dose level

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