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Through this integrated mechanism of action, mazdutide represents a new approach to treating obesity and related metabolic diseases, targeting not only how much patients eat, but also how efficiently their bodies burn and store energy

Specifically, individual treatment with the amylin agonist sCT or with the GLP-1R agonist, liraglutide, successfully decreased 24 h body weight change and food intake at 1, 3, 6 and 24 h post-injection (Fig

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PLoS ONE 13(3):e0193473 Strazzullo P, DElia L, Kandala N-B, Cappuccio FP (2009) Salt intake, stroke, and cardiovascular disease: meta-analysis of prospective studies