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Baseline covariates included demographics, adverse determinants of socioeconomic health, lifestyle factors, medical conditions and medications that are risk factors associated with NAION and optic nerve and visual pathway disorders, 33,34 prior prescriptions of antidiabetic medications, and medical encounters

GIP has been shown to decrease food intake while blunting the metabolic adaptive responses that usually occur with calorie restriction resulting in weight reductions, and when combined with GLP-1 receptor agonism, may result in greater effects on markers of metabolic dysregulation such as body weight, glucose and lipids

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