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The FDA label includes a boxed warning regarding thyroid C-cell tumors observed in rodent studies, contraindicating its use in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

This excitement seems justified given the major impact GLP-1s are already having across healthcare, and noting that Novo Nordisks semaglutide quickly gained regulatory approval and payor coverage after it similarly showed its impact on cardiovascular events

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Healthy Fats (In Moderation) Healthy fats support hormone balance and fullness, but larger amounts can worsen nausea on tirzepatide

This guide covers everything researchers and patients need to know about combining tirzepatide with levothyroxine