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Using a Large Genetic Biobank The research team worked with retrospective data derived from the Million Veterans Program, created by the VA and considered the largest genetic biobank in the world

GLP-1 is a hormone that regulates blood sugar levels and can be effective for weight loss due to the impact on appetite regulation and satiety

3 demonstrates that in the discovery cohort (GWAS-Catalog), the BWMR analysis revealed a statistically significant inverse association between GLP-1R gene expression and the risk of DR development (OR = 0.39, 95% CI: 0.240.62, P = 0.0001)

Lineage specific changes in the sequence and function have been described in hystricomorph rodents for the key metabolic gene insulin 31
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Cohen DA, Bhatia R