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DPP-4is have modest glucose-lowering effects and minimal body weight loss effects compared with GLP-1RAs [24]

However, if 5-Amino-1MQ also improves insulin sensitivity (as suggested in animal models), combined use particularly alongside insulin or sulfonylureas could theoretically increase the risk of low blood sugar to a clinically significant degree
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[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Nauck MA, Wefers J, Meier JJ

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Consider talking to a therapist or counselor if you need additional support in managing stress or emotional eating