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Studies show GLP-1s help decrease weight, improve metabolic complications, lower flares and stiffness, and may slow joint damage when combined with DMARDs or biologics

In people with type 1 diabetes, hyperglycemia seems to be the primary driver of kidney damage, and the kidney lesions observed typically show classical glomerulopathy

While the foundations of a healthy lifestyle will always begin with diet and exercise, and bariatric procedures can be the right choice for patients with the chronic health issues associated with severe obesity, GLP-1 receptor agonists provide another safe, effective, and measured approach

Fitch expressed optimism about the study's results

The breakthrough came from creating synthetic versions of these hormones engineered to resist breakdown

JAMA Netw Open 2022;5:e2231982.ArticlePubMedPMC 9