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doi: 10.1159/000369968 22 SharmaDVermaSVaidyaSKaliaKTiwariV
Potential reduction in obesity-related risks Losing weight through improved metabolism can lower the risk of heart disease, high blood pressure, and other complications
These features correspond to better initial responses to PD-1/PD-L1 inhibitors, although most patients ultimately develop resistance due to mechanisms such as activation of alternative checkpoints, reduced antigen recognition, T cell exhaustion, or metabolic dysregulation
J Nanobiotechnol 24 , 265 (2026)
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These symptoms typically diminish within 4-8 weeks as the body adjusts to the medication
