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Semaglutide may help slow or reverse prediabetes by promoting weight loss, supporting insulin secretion, and stabilizing blood sugar alongside lifestyle changes
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Interestingly, the concomitant administration of GLP-1 receptor agonists with a sulphonylurea in the in situ perfused rat pancreas led to uncoupling of the insulinotropic effect of GLP-1 from its glucose dependence [136]
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