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But the current evidence is limited: While GLP-1s may be linked to improvements in factors that drive MS disease activity, these are associations theres no clear proof that GLP-1s directly slow MS progression, she cautions

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Literature Search Strategy A structured literature search was performed across PubMed/MEDLINE, Embase, Scopus, Web of Science, and the Cochrane Library to identify relevant publications addressing body composition changes during GLP-1 receptor agonist therapy, the effects of testosterone and TRT on lean mass and skeletal muscle, and the intersection between metabolic weight loss and androgen physiology