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Retatrutide for the treatment of obesity: A phase 2, randomized, double-blind, placebo-controlled trial

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Collectively, these distinct yet complementary pathways provide a strong mechanistic rationale for the enhanced efficacy of multi-target agonists in treating the multifaceted pathophysiology of MASLD

N Engl J Med 384(12):11131124 Polyzos SA, Kountouras J, Zavos C, Deretzi G (2012) Nonalcoholic fatty liver disease: multimodal treatment options for a pathogenetically multiple-hit disease

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