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"While they all act on the same basic pathway, their efficacy, side effect profiles and cardiovascular benefits can vary significantly," she told Fox News Digital

The lack of benefit with lixisenatide is likely attributable to its shorter half-life and more modest effects on glycemia and weight compared to longer-acting agonists

Results from some in vitro studies have also reported a link between energy homeostasis with cardiovascular activity

Notably, the FDG tracer, a glucose analogue, is exquisitely sensitive to metabolic perturbations

Meaningful weight loss (5+ pounds) typically takes 4-8 weeks