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Finally, different weight loss medications raised concerns about suicidality in the past, including phentermine/topiramate, bupropion/naltrexone, and especially rimonabant, an inverse agonist for the cannabinoid receptor CB1, which was worldwide withdrawn for increased risk of suicidality.SGLT2 inhibitors for depression are a relatively new topic

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diabetic ketoacidosis (leads to changes in blood pH)

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If heart palpitations occur, they may decrease in frequency as the body adjusts to the medication, but at times, you may need to change your dose or stop taking the medication

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