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Silverii GA, Clerico A, Fornengo R, Gabutti G, Sordi V, Peruzzi O, et al

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Glucagon-Like Peptide-1 Receptor Activation in the Brain Concerning Inflammation Neuroinflammation is related to the chronic activation of microglia and astrocytes accompanied by significant cytokine and chemokine production, the infiltration of peripheral immune cells and edema formation, and increased BBB permeability or even breakdown (DiSabato et al., 2016

Conclusion The study was successfully completed within the stipulated timeline, without any deviations, and in compliance with the targated regulatory submission requirements