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Efficacy and Safety of Once-Weekly Dulaglutide Versus Insulin Glargine in Mainly Asian Patients With Type 2 Diabetes Mellitus on Metformin and/or a Sulphonylurea: A 52-Week Open-Label, Randomized Phase III Trial

In trials, retatrutide produced higher weight loss than Wegovy at the highest dose of each: 28.7% at 68 weeks on retatrutide 12 mg, versus 20.7% at 72 weeks on the newer Wegovy 7.2 mg dose, and 14.9% at 68 weeks on the older Wegovy 2.4 mg dose

GLP-3(Reta) is the most mechanistically complex compound in the class, which also means the most variables in play for experimental design

Never skip steps in the gradual dose escalation, even if youre tolerating lower doses easily

Glucagon-like peptide-1 receptor agonists and gastrointestinal cancer risk in individuals with type 2 diabetes