whats the difference between tirzepatide and ozempic vs. Semaglutide: What You Should Know How diabetes medications like semaglutide
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Studies have shown side effects like indigestion, dizziness and mildly elevated heart rate are common with GLP-1 analogs

On average, tirzepatide led to 20.2% weight loss compared to 13.7% with semaglutide over 72 weeks of treatment

Most people feel less hungry and may start to lose weight, though the dose usually starts low and steps up about every four weeks so your body adjusts and side effects stay manageable

Results vary based on individual factors such as starting weight, dosage, diet, physical activity, sleep, and overall health

Olasupo Odunsi, MD, Medical Director Reviewed July 5, 2026 Tirzepatide, sold as Mounjaro, has become one of the most talked about options for people trying to lose weight in Maryland and Virginia
