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Regulation and function of insulin and insulin-like growth factor receptor signalling

Expert Rev Endocrinol Metab

In mice, liraglutide blunts hypertension induced by angiotensin II (Ang-II), an effect that is absent in GLP-1R KO mice, and is also attenuated upon pretreatment of WT mice with exendin (939) [640]

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Pesquisadores das universidades de Angers e Ulster mostratam que h uma reduo massiva na fora ssea em camundongos knockout para o receptor de GLP-1, principalmente devido a baixa qualidade ssea