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This is especially true for patients who undergo more invasive procedures like a gastric bypass to get relief

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Phentermine may have a role in specific scenariossuch as short-term use (typically 12 weeks or less) in patients with no cardiac historybut evidence increasingly favors GLP-1 monotherapy as a first-line approach due to better safety margins and sustained weight loss

Our study included more recent RCTs on SGLT-2 inhibitors, such as the Sotagliflozin on Cardiovascular and Renal Events in Patients with Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk (SCORED) and Sotagliflozin on Cardiovascular Events in Patients with Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF) trials, which may have contributed to this mixed result

Researchers believed that the gut could directly signal to your pancreas

It's important to note that, like other weight loss medications, individuals may experience weight regain when they stop using Wegovy