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Adapting these studies to investigate how endocytosis inhibition impacts prolonged insulin secretion is challenging due to the nonspecific effects of chemical approaches 57 , as well as the role of dynamin in insulin granule exocytosis 58

F., & Ren, J

Pereira, M

Allison Koch MS, RD, CSSD, LDN is a vice president in FleishmanHillards Chicago office, where she provides nutrition communications counsel for clients

Side effects observed in Phase 2 studies include nausea, vomiting, diarrhoea, decreased appetite, and injection-site reactions

19 Administration of the 7nAChR agonist TC-7020 to Lepr db/db mice reduces weight gain, food intake and levels of blood glucose, HbA 1c and triglycerides