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The persistently elevated risk amongst these trial populations demonstrates the limitations of current management strategies and highlights the need for therapies that address the link between metabolic disease and direct cardiovascular pathology

Regul Pept 175:2129 [DOI] [PubMed] [Google Scholar] 55.Lu N, Sun H, Yu J, Wang X, Liu D, Zhao L, Sun L, Zhao H, Tao B, Liu J (2015) Glucagon-like peptide-1 receptor agonist liraglutide has anabolic bone effects in ovariectomized rats without diabetes

Plan the discontinuation carefully if you choose to stop

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16% identified as Hispanic or Latino ethnicity

A phase II RCT of lixisenatide in early PD, which was defined as patients recruited within 2 years of diagnosis, also demonstrated the promising disease-modifying effect of lixisenatide, particularly regarding motor disability