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Description
While effective, these treatments require monitoring due to potential side effects, especially in non-diabetic patients.This therapeutic advancement represents a revolution in the management of metabolic diseases and obesity.Despite their efficacy in managing obesity and metabolic disorders, GLP-1 and GIP receptor agonists can cause side effects, which are a common reason for therapy discontinuation

We used version 2 of the Cochrane risk-of-bias tool for randomised trials to assess risk of bias for the primary outcome

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However, research suggests that a high protein diet and resistance training may help prevent loss of muscle mass during GLP- 1 RA usage

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But the range was wide some lost over 25%, some less than 5%.