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Many clinical trial participants experienced 15-20% body weight reduction by this stage

Weight loss: About 10.8% body-weight reduction at 4.5 mg over 26 weeks in phase 2 [1]

One positive thing that typically stops when you discontinue the medication: the side effects, mainly gastrointestinal discomfort like nausea, says Matthew Hayes, a psychiatry professor at the Perelman School of Medicine at the University of Pennsylvania who studies neural signaling pathways in obesity

In a large 72-week study involving obese patients without diabetes, those who used tirzepatide lost 15-20% of their body weight

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Safety and Side Effects Like any prescription weight loss medication, Tirzepatide oral drops should only be taken under professional guidance