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This study has several limitations
In particular, experimental studies have demonstrated that manipulation of the gut microbiota can influence endogenous GLP-1 secretion and metabolic outcomes, indicating a mechanistic role for hostmicrobe interactions under controlled preclinical models ( Akkermansia muciniphila , a mucin-degrading bacterium associated with improved gut barrier function and reduced inflammation (120)
Effect of GLP-1 on heart rate (HR) and blood pressure (BP) GLP-1 effects on HR and BP are species-related
