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If calling and talking to someone is how you prefer to handle medical questions, that is a limitation
The actions of GLP-1 and GIP on different tissues are described below

Within 10 years of T2DM diagnosis, 24.9% of people develop microalbuminuria, 5.3% develop macroalbuminuria, and 0.8% develop advanced CKD that includes persistently elevated plasma creatinine or the need for renal replacement therapy [4]

Maintenance therapycontinuing a stable, effective dose long-termaligns with how weight loss medications are used in other therapeutic areas
Gastroenterology 167 , 402404 (2024)

Avoid caffeine and alcohol initially, as both increase fluid loss and can trigger or worsen loose stools
