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doi: 10.1016/j.cell.2024.06.003 124 RosenkildeMMLindquistPKizilkayaHSGasbjergLS

Please contact your doctor if you have any questions or concerns regarding your health

You might have found success with a GLP-1 medication but still struggle with persistent cravings, or perhaps you are just starting your journey and wondering if a combination approach is more effective

As well as, it has beneficial action in NASH (Non-alcoholic Steatohepatitis) treatment, which is connected with liver issues with obesity and type 2 diabetes

To compete effectively, there are a variety of approaches manufacturers may take to ensure patients can easily access their therapies

They draw water into the bowel, softening stools and increasing frequency Bulk-forming laxatives (ispaghula husk, methylcellulose) work similarly to dietary fibre and are generally suitable for long-term use, but should be avoided if you have severe bloating or suspected impaction Stimulant laxatives (senna, bisacodyl) should be reserved for short-term use when other measures fail Rectal treatments (glycerol suppositories, small-volume enemas) can provide rapid relief for occasional constipation Establishing a regular toilet routine can be beneficial