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The study focused on two genetic variants that affect the enzyme peptidyl-glycine alpha-amidating monooxygenase (PAM)

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Further analysis of single-cell RNA sequencing data in fibroblasts, detailed in Figure S5 , provides a more comprehensive view of the transcriptional changes

Ongoing Research : Phase 3 trials aim to assess cardiovascular and renal endpoints , including risk reduction for stroke , myocardial infarction , and chronic kidney disease

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