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Description
This perspective article proposes a conceptual framework for consideration and research validation.

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The World Health Organisation's 2026 global guidelines on GLP-1 therapies for obesity explicitly recommend combining medication with intensive behavioural interventions, including structured goal-setting for diet and physical activity

GLP-1 could change that.

Most people experience the greatest weight loss between weeks 16 and 30 of semaglutide therapy, with continued benefits possible into month 12 and beyond

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