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These include leptin sensitizers, Y2R agonists (Eli Lilly, Novo Nordisk), amylin/calcitonin dual agonists (Nordic Biosciences, Amylin Pharmaceuticals), and ghrelin-targeting agents (Noxxon, Cytos) Novel mechanisms : There are several companies taking differentiated (non-incretin) approaches to obesity

Ozempic (semaglutide) is a GLP-1 receptor agonist licensed in the UK for type 2 diabetes mellitus

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