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Data from the STEP clinical trials demonstrate that diarrhoea and other digestive side effects typically diminish significantly after the first 3-6 months of treatment, even with continued medication use

[DOI] [PubMed] [Google Scholar] 222
[DOI] [PubMed] [Google Scholar] 691.Labouesse M.A., Stadlbauer U., Weber E., Arnold M., Langhans W., Pacheco-Lopez G

Available at: Masson W, Lobo M, Nogueira JP, Barbagelata L, Touzas P, Fras JP
Sridhar VS, Dubrofsky L, Boulet J, Cherney DZ

Its become important to ask if these medications interact with antidepressantssince the rate of antidepressant use is also on the rise