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Slowed gastric emptying means gels and drink mix take longer to absorb during races

Nausea occurred in about 28% of participants at the 12 mg dose, which is notably lower than Semaglutides 44% nausea rate

Studies have noted higher rates of gastrointestinal disorders, hypotension, syncope, kidney stones (nephrolithiasis), interstitial nephritis, and drug-induced pancreatitis

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Long-term considerations: Understanding potential long-term effects, both positive and negative, informs research decisions

A 2019 review in *Obstetrics & Gynecology* noted that any medication significantly slowing GI transit warrants contraceptive counseling, particularly for women using lower-dose formulations