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Clinical evidence from semaglutide trials shows cumulative weight loss of 815 pounds by the end of week 12 in patients who maintain consistent eating habits

Some patients experience medication simplification as their A1C normalizes: a person on three oral diabetes drugs plus insulin may eventually reduce to semaglutide alone or semaglutide plus one other agent

The company claims that females using Mirena to ease heavy menstrual bleeding showed an 80% reduction in bleeding after 3 months

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The combination lacks clinical trial data establishing safety and efficacy