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[38] Live or live-attenuated vaccines should generally not be administered to patients receiving immunosuppressive doses of prednisone due to the potential for vaccine-induced infections

Chen K, Yan J, Suo Y, Li J, Wang Q, Lv B

[1] [2] It is prescribed as an adjunct to a reduced-calorie diet and increased physical activity

Nonetheless, it should be taken at the same time every week

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If someone is struggling with persistent nausea or diarrhea at their current dose, the provider can hold or even temporarily reduce the dose rather than pushing forward