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February 2025: Novo Nordisk announced that semaglutide 2.4 mg would be available in Mexican pharmacies by April 2025, with an average 17.5% weight loss observed in pivotal trials

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If you're taking insulin or certain diabetes drugs like sulfonylureas (glipizide or glyburide), these can cause weight gain

Patients with certain GLP1R variants may achieve stronger appetite suppression at lower doses, while others may benefit from higher titration

For this, the Patient Health Questionnaire-9 (PHQ-9) [100] could be used, which consists of 9 items

A 2026 preprint went big, analyzing more than 6,400 grey-market samples across fourteen compounds, retatrutide among them
