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Improved quality of life: Obesity is associated with a number of negative health outcomes, including increased risk of heart disease, diabetes, and certain cancers

doi: 10.1093/EURHEARTJ/EHAA082 119 BatistaAFBodart-SantosVDe FeliceFGFerreiraST

Dehydration and electrolyte disturbances: Gastrointestinal side effects, particularly vomiting and diarrhea, can lead to dehydration and electrolyte imbalances

However, in addition to a lack or ambiguity of similar findings in humans, GLP-1 RAs are resistant to enzymatic cleavage as noted earlier (Mller et al., 2019

Third-line: GLP-1 agonists like semaglutide

The key is designing the cost-share to discourage casual use while keeping the medication affordable for employees who are clinically committed to treatment