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Notably, in those with a personal or family history of medullary thyroid carcinoma, GLP-1 medications are contraindicated, due to the theoretical risk for medullary thyroid cancer (which has not been proven in human subjects) [9]
Impact of glucagon-like peptide-1 receptor agonists on adiponectin concentrations: A meta-analysis of randomized controlled trials
Yao et al., 2019)
In diabetic cardiomyopathy, energy metabolism in cardiomyocytes may be impaired due to factors such as hyperglycemia and insulin resistance
The essential role of insulin-like growth factor-1 in the intestinal tropic effects of glucagon-like peptide-2 in mice
On average, people in the study were over age 65, more than 70% were White, and more than 92% were men, so the study results may not apply to other types of GLP-1 users
