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insurance companies often refuse to cover them after a period of time, resulting in patients stopping the drugs

Core weight management practices are still recommended as most insurances require demonstration of a concerted effort and some weight loss success before approval for surgery

2022;117:e1289

TPH1 is also expressed at other locations to synthesize serotonin for local physiological functions

Patients should seek immediate medical attention for severe, persistent abdominal pain radiating to the back

Several potential pathomechanisms seem to be critical in prostate cancer pathogenesis in obese individuals: (1) chronic inflammation within adipose tissue surrounding the prostate gland, which intensifies local and systemic inflammatory response, (2) hyperinsulinemia due to excess adipose tissue and obesity, and (3) increased levels of adipokines as a consequence of increased PPAT [41]