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In Phase II data released this week, people taking a monthly dose of PF3944 continued to lose more weight than those on a placebo.

Orthostatic hypotension is associated with a significant increase in cardiovascular risk and falls, and up to a 50% increase in relative risk of all-cause mortality

Cessation is consistently linked to rebound weight gain, and retrospective data suggest greater gestational weight gain and higher risks (e.g., preterm delivery, GDM, hypertensive disorders) after stoppingthough causality remains uncertain

A new deal between the White House and pharmaceutical companies like Novo Nordisk and Eli Lilly is shaking things up.

The mechanisms underlying weight lossinduced bone loss are complex and multifactorial