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While effective, these treatments require monitoring due to potential side effects, especially in non-diabetic patients.This therapeutic advancement represents a revolution in the management of metabolic diseases and obesity.Despite their efficacy in managing obesity and metabolic disorders, GLP-1 and GIP receptor agonists can cause side effects, which are a common reason for therapy discontinuation

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The ARISE-HF trial enrolled 691 patients (median age 67 years), of whom half were women, at 62 sites around the world

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Both applications, which were filed under the FDAs generic pathway, address all indications of the reference medicines, Mounjaro and Zepbound