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Last reviewed: July 8, 2026 Last updated: July 8, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

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doi:10.1007/s13300-017-0353-5

10.1080/14712598.2019.1618266 22 MolagodaI

As GLP-1s can cross the blood-brain barrier and have a direct effect on brain function, it is important to examine their impact on mental health, especially in patients with mental illness. Researchers conducted a systematic review of studies assessing the impact of GLP-1s on mental health and metabolic outcomes in people with and without a mental illness between 2010 and August 2024