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GLP1-RAs seem promising for effective treatment of obese PCOS patients, acting on one of the primary causes of PCOS at the molecular level

By focusing on two specific representatives of two distinct classes of weight reducing agents, liraglutide and FGF21, in combination with our monoclonal leptin neutralizing antibodies, we demonstrate that leptin reduction acts as a common mechanism for weight loss and improvement in metabolic disorders, including diabetes and liver fibrosis

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Managing diabetes and maintaining appropriate weight gain are crucial during pregnancy

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Specific symptoms, such as overtalkativeness manifesting as flight of ideas, are more distinctive of mania, and guilt is more unique to depression