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8 Faculty of Medicine and Pharmacy, University of Oradea, Oradea, 410073, Romania

Peptides, 125 , 170213

Like other GLP-1 medications, it works best when paired with lasting lifestyle changes such as healthy eating, regular activity, and long-term habit support

These results suggest that GLP-1RAs may be preferred to sulfonylureas as an add-on therapy [65]

In most cases, dysesthesia events were mild and rarely led to treatment being stopped, but it is something prescribers will continue to monitor closely as further trial data becomes available

Therefore, almost all scientific guidelines now recommend specific treatments for patients with type 2 diabetes based on CVOTs data, namely adding to metformin a SGLT-2 inhibitor or a GLP-1RA with proven CV disease benefit in patients with type 2 diabetes and CV disease, established kidney disease, or HF [7,8,9,10]