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While dedicated endometriosis trials have not yet been completed, the mechanism is consistent with benefits seen across the GLP-1 class and early observational data from women in trial settings has included reports of reduced pelvic pain and inflammation

GLP-1 exerts its biological effects by binding to a specific receptor (GLP-1R), which is expressed in different types of peripheral tissues and in the central nervous system [12]

It follows that the use of incretinomimetics activating the GLP-1R pathway may be an interesting lead for treating OA

Impact of pharmacist intervention to improve medication access for patients with diabetes

Gradual Tapering Research indicates that abruptly stopping GLP-1 medications can lead to a resurgence of appetite and potential weight gain

Bertilsson, G
