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Offer subcutaneous semaglutide up to 1 mg once weekly for CV, renal and glycaemic benefits (no specific guidance on tirzepatide or oral semaglutide because CVOT results were unavailable at time of review)

PMID 20727946

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Multiple studies with FGF21 and FGF21 analogs demonstrate robust control of glucose and body weight reduction in preclinical studies

[00:10:18] Emily Field: A very commonly suggested rate is about 0.5 to 1% of body weight lost per week