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The researchers projected that the participants would return to their original weight in 18 months

Long-term use may be required to maintain weight loss, which has cost and ongoing commitment implications

For weight management, the FDA labels these drugs as treatments for chronic obesity, intended for continued use

For people with type 2 diabetes, Ozempic and Mounjaro may increase the risk of damage to the eyes (diabetic retinopathy)

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A large observational study published in Diabetologia in 2022 looked at GLP-1 receptor agonist use in humans and found no statistically significant increase in thyroid cancer risk