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Metalloproteinases are extracellular matrix remodeling enzymes, and any change in their regulatory mechanism may contribute to complications in T1DM 42

See section 2 of the patient information leaflet for a full list of warnings

Dautres essais cliniques sont en cours pour valuer les bnfices du smaglutide dans diverses complications de lobsit telle que linsuffisance rnale et linflammation hpatique

This proactive approach ensures that any potential concerns are addressed promptly, maximizing the benefits of the treatment while minimizing risks

doi: 10.1016/j.jacc.2024.11.001 [DOI] [PubMed] [Google Scholar] 207.Wadden TA, Chao AM, Machineni S, et al