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Given its complexity, effective obesity management necessitates a multidisciplinary, individualized approach that combines nutritional and behavioral interventions, physical activity, pharmacological therapies, and metabolic-bariatric surgery when indicated

Lastly, we present considerations to accurately interpret these data and outline key knowledge gaps for further investigation

Asia Pacific is projected to witness rapid growth at a 14.1% CAGR

10.1016/j.cmet.2014.04.005 114 StefaterM

Unfortunately, NAFLD is often underdiagnosed because of its asymptomatic nature, the absence of standardized diagnostic assays in everyday clinical practice and the lack of awareness among individuals and physicians (less than 5% of individuals with NAFLD are aware of their disease) [1, 6, 9]

Additionally, those practicing intermittent fasting experienced improved insulin sensitivity, further supporting blood sugar stability and weight management
