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Given its complexity, effective obesity management necessitates a multidisciplinary, individualized approach that combines nutritional and behavioral interventions, physical activity, pharmacological therapies, and metabolic-bariatric surgery when indicated

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Lastly, we present considerations to accurately interpret these data and outline key knowledge gaps for further investigation

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Asia Pacific is projected to witness rapid growth at a 14.1% CAGR

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10.1016/j.cmet.2014.04.005 114 StefaterM

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Unfortunately, NAFLD is often underdiagnosed because of its asymptomatic nature, the absence of standardized diagnostic assays in everyday clinical practice and the lack of awareness among individuals and physicians (less than 5% of individuals with NAFLD are aware of their disease) [1, 6, 9]

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Additionally, those practicing intermittent fasting experienced improved insulin sensitivity, further supporting blood sugar stability and weight management

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