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Despite the regular exercise and careful diet, the 44-year-old from Mesa has struggled with her weight for years

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Because SCFA production depends on microbiome and diet, GLP-1 medications alone cannot rebuild this pathway

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Karagiannis T, Tsapas A, Athanasiadou E, Avgerinos I, Liakos A, Matthews DR, et al

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To summarize several meta-analyses of CVOTs conducted with GLP-1RAs, it isconfirmed that based on 43 trials, GLP-1RAs are a class of efficacious agent for reducing MACE (MH-OR 0.87 [0.83, 0.92]), cardiovascular and all-cause mortality (MH-OR 0.89 [0.83, 0.96]) [48]

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