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doi: 10.1007/s10654-018-0366-z
It was the most effective antidiabetic agent anyone had ever seen, says Andrew Young, former vice president of research at Amylin Pharmaceuticals, the San Diegobased company that brought Byetta to market
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Furthermore, low-grade inflammation of the endothelium is an early event in the pathogenesis of atherosclerotic cardiovascular disease and the GLP-1 analog liraglutide was shown to exhibited anti-oxidative and anti-inflammatory effects, including upregulation of anti-oxidative enzymes and inhibition of nuclear factor kappa B (NF-B)-signaling on endothelial cells (67, 77)
SUSTAIN-6, trial to evaluate cardiovascular and other long-term outcomes with semaglutide in subjects with type 2 diabetes
doi: 10.1007/s00125-022-05715-4 [DOI] [PMC free article] [PubMed] [Google Scholar] 131
