glucagon like peptide 1 glp 1 agonists Cardiovascular Effects of Glucagon-Like Peptide-1 Receptor Glucagon-like peptide-1 - Wikipedia
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Outcomes included total and early-phase (060min) areas under the curve (AUCs) and peak concentrations
Janet Klein, MS RDN, CDN, CDCES, Bariatric Surgery and Obesity Medicine Program Director
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Conclusion GLP-1RAs show significant promise as a potential disease-modifying therapy for neurodegenerative and inflammatory eye diseases, acting through both systemic metabolic improvements and direct ocular mechanisms, representing a paradigm shift beyond their metabolic indications.
Risk of bias: all four RCTs were rated low risk by RoB2 (with some concerns for open-label outcome ascertainment in three trials, a domain-specific issue that does not alter the overall RoB2 category from low)
